Upload natively to each app rather than cross-posting a watermarked file through a third-party scheduler that slaps another logo on. Use 9:16 1080p. Publish the six variants spaced enough that they are not six identical thumbnails in a row, but close enough that you can compare a 48-hour window. Do not edit the video after you might need the post ID for Spark or boosting.
TikTok and Instagram will not rank the same hook the same way, and that disagreement is useful rather than annoying. A complaint hook that holds on TikTok and dies on Reels is a platform note, not a reason to delete the product. Keep a sheet: post URL, hook code, avatar, publish time, and later organic views, average watch, comments, shares, saves. You will need those URLs to generate authorization codes or to boost, and you will not remember which hook was which from a thumbnail a week later in a busy camera roll.
Hashtags are not a strategy. A few relevant ones beat a block of twenty that reads as 2019 spam. Location and collabs only if they are true. Do not ask a creator to seed your AI avatar video as if it were their footage — that is a trust problem and usually a rights problem. Seed from handles you control. If you later whitelist a human creator, that is a different workflow with their authentic post, not a deepfake of their face, and you should not mix those objects in the same 'seed' column of the sheet.